Reprogramming Stars #13:Establishing Connections with Cellular Reprogramming–An Interview with Dr. Daniella Rylander Ottosson

Reprogramming Star: Dr. Rylander Ottosson is an Associate Professor at the Lund University and Wallenberg Academy Fellow. The Ottosson laboratory studies cell fate specification toward GABAergic interneurons from human neuronal progenitor cells and somatic cells using neuronal differentiation and reprogramming approaches. The long-term goal is in brain repair and rewiring of altered brain plasticity in disorders such as Schizophrenia and Alzheimer’s disease. Her laboratory includes cell-based models, mouse in vivo model, and human organotypic cultures with a clear focus on the functional and integrational aspects of in vivo reprogrammed cells. In parallel the laboratory applies in vitro reprogramming of patient skin fibroblast to develop interneuron disease models for pathologies related to these neurons.