Reprogramming.
Hematopoiesis.
Immunity.

Lab

We are studying how hematopoietic cell fate is specified, maintained, and eventually modified or reversed. Inspired from the fields of stem cell biology, immunology, and cancer we use an interdisciplinary approach to mechanistically understand hematopoietic and immune cell identities and translate our findings into novel gene and cell therapies.

Research

Merging Stem Cells with Immunology by Cell Fate Reprogramming. Learn more about our research lines:

Latest Publications

Single-Cell Transcriptional Profiling Informs Efficient Reprogramming of Human Somatic Cells to Cross-Presenting Dendritic Cells

Fábio F. Rosa, Cristiana F. Pires, Ilia Kurochkin, Evelyn Halitzki, Tasnim Zahan, Nejc Arh, Olga Zimmermannová, Alexandra G. Ferreira, Hongzhe Li, Stefan Karlsson, Stefan Scheding, Carlos-Filipe Pereira

March 4, 2022 / Vol. 7, No. 69
Science Immunology

Cell Fate Reprogramming in the Era of Cancer Immunotherapy

Olga Zimmermannova, Inês Caiado, Alexandra G. Ferreira and Carlos-Filipe Pereira

July 21, 2021 / Volume 12, Article 714822
Frontiers in Immunology

Team

We are a diverse group – molecular biologists, MDs, PharmDs, tumor immunologists, stem cell biologists and computational scientists – at all career stages. We architect strategies to dissect and manipulate immune cell identity.

Looking for an opportunity? Join our international team!

Latest News

Camila Vazquez Echegaray Awarded a MSCA Postdoctoral Fellowship

Pereira Lab researcher Camila Vazquez Echegaray was awarded a Marie Skłodowska-Curie Actions (MSCA) Postdoctoral Fellowship.

Eurostars-funded REPRINT Project Kick-off Meeting

The Pereira Lab took part in a meeting held by Asgard Therapeutics AB, together with consortium members InSphero and Antineo, that sets the official kick-off to the earlier announced Eurostars project.

Encoding Human Dendritic Cell Fate

PU.1, IRF8, and BATF3 cooperation and role in inflammatory signaling during programming of human cDC1-like cells was uncovered at the Pereira Lab.