Reprogramming.
Hematopoiesis.
Immunity.
Lab
We are studying how hematopoietic cell fate is specified, maintained, and eventually modified or reversed. Inspired from the fields of stem cell biology, immunology, and cancer we use an interdisciplinary approach to mechanistically understand hematopoietic and immune cell identities and translate our findings into novel gene and cell therapies.
Research
Merging Stem Cells with Immunology by Cell Fate Reprogramming. Learn more about our research lines:
Latest Publications
A combinatorial transcription factor screening platform for immune cell reprogramming
Ilia Kurochkin, Abigail R. Altman, Inês Caiado, Diogo Pértiga-Cabral, Evelyn Halitzki, Mariia Minaeva, Olga Zimmermannová, Luís Henriques-Oliveira, Dominik Klein, Malavika Nair, Daniel Oliveira, Laura Rabanal Cajal, Ramin Knittel, Cora Feick, Markus Ringnér, Marcel Martin, Branko Cirovic, Cristiana F. Pires, Fabio F. Rosa, Ewa Sitnicka, Fabian J. Theis, Carlos-Filipe Pereira
January 14, 2026 / 17
Cell Systems
Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity
Luís Henriques-Oliveira*, Abigail R. Altman*, Ilia Kurochkin*, Ervin Ascic, Evelyn Halitzki, Andreea-Medeea Matei, Diogo Pértiga-Cabral, Isabel Ulmert, Signe Holst, Malavika Sreekumar Nair, Pedro P. Cunha, Sun-Mi Park, Stefano Vergani, Michael G. Kharas, Joan Yuan, Katharina Lahl, Fábio F. Rosa, Cristiana F. Pires, Carlos-Filipe Pereira
August 29, 2025 / 58
Immunity
In Vivo Dendritic Cell Reprogramming for Cancer Immunotherapy
Ervin Ascic, Fritiof Åkerström, Malavika Sreekumar Nair, André Rosa, Ilia Kurochkin, Olga Zimmermannova, Xavier Catena, Nadezhda Rotankova, Charlotte Veser, Michal Rudnik, Tommaso Ballocci, Tiffany Schärer, Xiaoli Huang, Maria de Rosa Torres, Emilie Renaud, Marta Velasco Santiago, Özcan Met, David Askmyr, Malin Lindstedt, Lennart Greiff, Laure-Anne Ligeon, Irina Agarkova, Inge Marie Svane, Cristiana F. Pires, Fábio F. Rosa, and Carlos-Filipe Pereira
September 5, 2024
Science
Team
We are a diverse group – molecular biologists, MDs, PharmDs, tumor immunologists, stem cell biologists and computational scientists – at all career stages. We architect strategies to dissect and manipulate immune cell identity.
Looking for an opportunity? Join our international team!
Funders
Latest News
The Pereira lab publishes “Canonical and isomiR products of miR-142 enhance dendritic cell reprogramming” in Cell Reports
We are thrilled to announce the publication of our article “Canonical and isomiR products of miR-142 enhance dendritic cell reprogramming” in Cell Reports.
The Pereira Lab as immune cell engineers – funding from the Chan Zuckerberg Biohub Network and the Chan Zuckerberg Initiative
Earlier this year, the Chan Zuckerberg (CZ) Biohub Network and the Chan Zuckerberg Initiative (CZI) funded the project “A ‘sense-and-reprogram’ platform for systemic cancer immunotherapy”, a joint initiative from the Pereira Lab and the laboratory of Axel Hyrenius-Wittsten (co-PI) at Lund University. This week, the Pereira Lab celebrates this research project by attending the New York Symposium on Immune Cell Engineering and Reprogramming hosted by Biohub.
The Pereira Lab published a STAR Protocols paper
The Pereira Lab published a STAR Protocols method entitled “Protocol for identifying cellular reprogramming minimal networks using combinatorial transcription factor screening”.
